"Journal club: A fluorescent-protein spin qubit"

Speaker: Jingjiao Guan

Abstract

Fluorescent proteins are foundational tools in biology, widely used to visualize gene expression, protein localization, and dynamic cellular processes. Recent work has revealed that enhanced yellow fluorescent protein (EYFP) also exhibits quantum-coherent spin properties, suggesting an unexpected role as a genetically encodable qubit. In this talk, I will introduce the biological and molecular foundations of fluorescent proteins, including chromophore chemistry, triplet-state photophysics, and plasmid-based methods for engineering new variants. I will then review the EYFP qubit study, emphasizing its microwave-driven spin transitions and optically detected magnetic resonance enabled by the long-lived triplet manifold. These discoveries position EYFP as a unique, biologically integrated quantum sensor with capabilities previously limited to solid-state systems such as NV-center diamonds. Finally, I will explore potential applications of EYFP-based qubits in quantum biosensing within living cells.

Quantum Bites is a new monthly brown bag seminar to spark connections, share exciting breakthroughs and grow a vibrant community in Quantum Information Science and Engineering (QISE). It’s a space to exchange ideas, explore cutting-edge research and inspire collaborations across disciplines. Whether deep into quantum research or just curious, you’ll leave each session with fresh perspectives and new connections.

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